Khan Computational Imaging Lab

I am a Scientist at the Robarts Research Institute and Assistant Professor in the Department of Medical Biophysics and Medical Imaging at Western University.  I obtained my PhD from Simon Fraser University and joined Western University in 2011 as a post-doctoral fellow. My research is focussed on the development of intelligent image processing and analysis technologies, and their application in the diagnosis and treatment of neurological disorders.

Google Scholar Publications

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Robarts Profile

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I am a postdoc at Robarts Research Institute at Western University, London. I obtained my Ph.D. from Memorial University in theoretical physics with a focus on black holes. My MSc was in theoretical astrophysics from the University of Waterloo and BSc in physics from McMaster University. My research focuses on diffusion MRI (dMRI), and my current projects aim to model diffusion processes in geometrically complex regions of the brain like the neocortex and the hippocampus. We employ techniques from differential geometry to flatten these complex regions and then model diffusion processes in the flattened space in order to enhance detection of abnormalities from dMRI.

Postdoctoral fellow (CONP research scholar), co-supervised with Dr.Ali Khan & Dr. Corey Baron

My work focuses on in vivo characterization of the cortex using multi-parameter quantitative imaging at 7 Tesla. Here, I'm both interested in the brain's normal population anatomical variability, as well as how these measures change due to disease. Current projects involve quantification of the hippocampal formation's vascularization using high-resolution ASL, arterial maps and venograms, and how these can be used to improve its functional characterization

Postdoctoral fellow ( BrainsCAN ), co-supervised with Dr.Ali Khan & Stefan Kohler

My research focuses on applying advanced MRI techniques to quantify brain microstructure in patients with neuropathological disorder and diseases. I am currently investigating the ability of a higher order tensor model called diffusion kurtosis imaging, aiming to better characterize brain tissue of temporal lobe epilepsy patients ultimately leading to accurate diagnosis and treatment.

Education:

1. BSc and PGDip in Physics, University of Papua New Guinea

2. MEng in Biomedical Engineering, Huazhong University of Science & Technology, China

Awards & Scholarships:

1. Western Graduate Research Scholarship

PhD student, Biomedical Engineering, jointly co-supervised with Terry Peters

Neurosurgery Resident, PhD student (co-supervised Terry Peters)

My work has focused on developing a topological coordinate framework for the hippocampus, a highly convoluted brain structure that is critical in memory, navigation, and affected by many neurological disorders. I have now applied this coordinate framework to MRI and histological datasets in search of anatomical details that correlate with cognitive variables or disease onsets.

PhD student, Neuroscience, co-supervised with Dr.Ali Khan & Stefan Kohler

I am a PhD student in the Department of Medical Biophysics. I completed my undergraduate degree in Electrical & Biomedical engineering at McMaster University before first joining the lab as a summer research student. My research is primarily focused on investigating the brain's short-range structural connections which join together nearby regions using multi-parametric MRI techniques.

PhD student, Medical Biophysics, supervised by Dr. Ali Khan

I am a PhD student in the Neuroscience graduate program. I received my BSc from University of Pittsburgh and MSc from the University of Texas at Dallas both in Neuroscience. My past research work has focused on memory and how it is effected by healthy aging as well as neurological diseases. Currently, I am working on quantitative MRI modelling of healthy ageing.

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Awards & Scholarships: BMI International Graduate Student Scholarship

PhD student, Neuroscience, co-supervised with Dr.Ali Khan & Dr. Taylor Schmitz

I am a Ph.D. student in the School of Biomedical Engineering at UWO. I completed my undergraduate degree in Physics from the University of Peradeniya in Sri Lanka and I obtained my MSc. in Astrophysics from the University of Western Ontario. My current research project is focused on analyzing the structural connectivity of the brain using Diffusion MRI to find a biomarker for Parkinson’s disease.

PhD. student, Biomedical Engineering. co-supervised by Dr. Ali Khan & Dr. Penny MacDonald

My research focuses on using functional MRI and a novel behavioural paradigm to probe Pattern Separation outside of the Ventral Visual Stream.

Awards and Scholarships:

1. NSERC USRA, Summer 2017

2. Ontario Graduate Scholarship, Sept 2018

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MSc., Neuroscience, co-supervised Dr.Ali Khan & Dr.Stefan Kholer

I am a MESc candidate in the School of Biomedical Engineering. I completed his undergraduate degree in Biomedical and Electrical Engineering at McMaster University. In my undergraduate, I had the opportunity to learn about multi-modal imaging techniques and their use in diagnostics and surgical intervention. My current research involves working on a novel technique that will highlight malformations seen within the cortex of patients with epilepsy using high-resolution histology. Hossein is the recipient of the Ontario Graduate Scholarship (2018).

MESc, Biomedical Engineering, supervised Dr. Ali Khan

I am a Master’s candidate in the Division of Clinical Anatomy through the Anatomy and Cell Biology Department. I received my undergraduate degree in Medical Cell Biology at Western University before starting my Master’s where I joined the Khan Lab. My Master’s research involves the creation and evaluation of a 3D histological atlas using Ultra-High Field registration of a post-mortem cadaveric brain in order to develop a potential model for DBS surgical planning.​

M.Sc, Clinical Anatomy, Supervised by Ali Khan

I am a MESc student in the School of Biomedical Engineering. I completed my undergraduate degree at the University of Waterloo in Systems Design Engineering. At Waterloo I had the opportunity to work with medical image processing and 3D printing with novel materials for biomedical purposes. I am currently working on development of physical phantoms for validation of diffusion MRI protocols.

MESc, Biomedical Engineering, supervised Dr. Ali Khan

I am an undergraduate electrical engineering student at Western University. My work so far has focused on creating reproducible software pipelines and shareable datasets. I have applied these tools to study geometric distortion in MRI and trajectory accuracy analysis for stereoelectroencephalography (SEEG).

BEng, Electrical Engineer, Supervised by Ali Khan

I am a third year undergraduate student in Medical Sciences. I will be working on cortical segmentation and quantification in 9.4T MRI.

Work-study Undergraduate student, Medical sciences

I'm a first-year undergraduate student in medical sciences. I'm interested in developing methods to understand the brain's microstructure through imaging. I'm working on diffusion MRI validation.

Medical Science undergraduate, Supervised by Dr.Khan and Dr.Baron

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Masters in Neuroscience (graduated Summer 2017), currently Staff Epileptologist Halifax (Dalhousie)

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Histology Technologist, retired

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Diagnostic Radiology Resident

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Medical Student, Schulich Research Opportunities Program, currently Neurosurgery Resident UWO

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Masters in Biomedical Engineering (graduated Summer 2016), currently R&D Engineer at Clearpath Robotics

Undergraduate NSERC USRA, currently Medical Student at McMaster University

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Masters in Biomedical Engineering (graduated Spring 2017), currently Research Coordinator at OBI

Visiting medical student (Chengdu, China)

Undergraduate Honors Thesis, Medical Biophysics

Undergraduate Honors Thesis, Neuroscience